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New Antibiotic Resistance Gene Was Detected in Livestock Bacteria in the USA

BLAIMP-27 antibiotic resistance gene (β-lactamase imipenemasa) conferring resistance to carbapenems, antibiotics of one of the most important classes, was detected in bacteria isolated from feeding pigs as well as from swabs taken from floors and walls of pig houses and from pig feces samples.

Therewith, use of carbapenems in animals is banned in the USA since this group of antibiotics is included in the first range of medicines used for human treatment.

Emergence of carbapenem-resistant bacteria may result from legal use of β-lactamase antibiotics not included in the group of carbapenems in animal farming. Bacteria are supposed to become carbapenem-resistant due to use of ceftiofur from group of cephalosporins.

BLAIMP-27 gene is easily transmitted from one bacterium to another one with plasmids that are small DNA fragments. Possible incorporation of this gene in the genome of microorganisms causing human diseases will make use of antibiotics of carbapenem group ineffective. Carbapenems are antibiotics applied for medical treatment of human infectious diseases. They are important drugs for combating bacteria resistant to other antimicrobials. Carbapenem-resistant bacteria pose a significant threat for humans as potential agents of hospital infections. The Rosselkhoznadzor monitors the situation.


Dec 27, 2016

Categorys: Veterinary